What is fibromyalgia?
What Is Fibromyalgia?
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Fibromyalgia - Wikipedia, the free encyclopedia
** Fibromyalgia **
From Wikipedia, the free encyclopedia
Jump to: navigation, search
/Classification and external resources/
The location of the nine paired tender points that comprise the 1990
American College of Rheumatology criteria for fibromyalgia.
eMedicine med/790 med/2934 ped/777 pmr/47
*Fibromyalgia* (*FM* or *FMS*) is characterised by chronic widespread pain
and allodynia (a heightened and painful response to pressure).^ Its
exact cause is unknown but is believed to involve psychological, genetic,
neurobiological and environmental factors.^^^ Fibromyalgia
symptoms are not restricted to pain, leading to the use of the alternative
term *fibromyalgia syndrome* for the condition. Other symptoms include
debilitating fatigue, sleep disturbance, and joint stiffness. Some
patients^ also report difficulty with swallowing,^bowel and bladder
abnormalities,^numbness and tingling,^ and cognitive dysfunction.^
Fibromyalgia is frequently comorbid with psychiatric conditions such as
depression and anxiety and stress-related disorders such as posttraumatic
stress disorder.^^ Not all fibromyalgia patients experience all
associated symptoms.^ Fibromyalgia is estimated to affect 2â4% of
the population,^ with a female to male incidence ratio of approximately
9:1.^ The term "fibromyalgia" derives from new Latin, /fibro-/, meaning
"fibrous tissues", Greek /myo-/, "muscle", and Greek /algos-/, "pain"; thus
the term literally means "muscle and connective tissue pain".
There is evidence that environmental factors and certain genes increase the
risk of developing fibromyalgia â these same genes are also associated
with other functional somatic syndromes and major depressive disorder.^
The central symptom of fibromyalgia, namely widespread pain appears to
result from neuro-chemical imbalances including activation of inflammatory
pathways in the brain which results in abnormalities in pain
processing.^ The brains of fibromyalgia patients show functional and
structural differences from those of healthy individuals
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