What are rabies?
What Is Rabies? What Causes Rabies? - Medical News Today
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Rabies - Wikipedia, the free encyclopedia
** Rabies **
From Wikipedia, the free encyclopedia
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For other uses, see Rabies (disambiguation).
/Classification and external resources/
Dog with rabies.jpg
Dog with rabies in the paralytic (post-furious) stage
eMedicine med/1374 eerg/493 ped/1974
*Rabies* (/ËreÉªbiËz/; from Latin: /rabies/, "madness") is a viral
disease that causes acute encephalitis in warm-blooded animals.^ The
disease is zoonotic, meaning it can be transmitted to humans from another
species (such as dogs), commonly by a bite from an infected animal. For a
human, rabies is almost invariably fatal if postexposure prophylaxis is not
administered prior to the onset of severe symptoms. The rabies virus
infects the central nervous system, ultimately causing disease in the brain
The rabies virus travels to the brain by following the peripheral nerves.
The incubation period of the disease is usually a few months in humans,
depending on the distance the virus must travel to reach the central
nervous system.^ Once the rabies virus reaches the central nervous
system and symptoms begin to show, the infection is virtually untreatable
and usually fatal within days.
Early-stage symptoms of rabies are malaise, headache and fever, progressing
to acute pain, violent movements, uncontrolled excitement, depression, and
hydrophobia.^ Finally, the patient may experience periods of mania and
lethargy, eventually leading to coma. The primary cause of death is usually
Rabies causes about 55,000 human deaths annually worldwide.^ 95% of
human deaths due to rabies occur in Asia and Africa.^ Roughly 97% of
human rabies cases result from dog bites.^ In the United States, animal
control and vaccination programs have effectively eliminated domestic dogs
as reservoirs of rabies.^ In several countries, including
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