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Malaria - Wikipedia, the free encyclopedia


** Malaria **

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/Classification and external resources/
A /Plasmodium/ in the form that enters humans and other vertebrates from
the saliva of female mosquitoes (a sporozoite) traverses the cytoplasm of a
mosquito midgut epithelial cell.
ICD-10 B50-B54
ICD-9 084
OMIM 248310
DiseasesDB 7728
MedlinePlus 000621
eMedicine med/1385 emerg/305 ped/1357
MeSH /C03.752.250.552/

*Malaria* is a mosquito-borne infectious disease of humans and other
animals caused by parasitic protozoans (a type of unicellular
microorganism) of the genus /Plasmodium/. Commonly, the disease is
transmitted via a bite from an infected female /Anopheles/ mosquito, which
introduces the organisms from its saliva into a person's circulatory
system. In the blood, the protists travel to the liver to mature and
reproduce. Malaria causes symptoms that typically include fever and
headache, which in severe cases can progress to coma or death. The disease
is widespread in tropical and subtropical regions in a broad band around
the equator, including much of Sub-Saharan Africa, Asia, and the Americas.

Five species of /Plasmodium/ can infect and be transmitted by humans. The
vast majority of deaths are caused by /P. falciparum/ and /P. vivax/,
while /P. ovale/, and /P. malariae/ cause a generally milder form of
malaria that is rarely fatal. The zoonotic species /P. knowlesi/,
prevalent in Southeast Asia, causes malaria in macaques but can also cause
severe infections in humans. Malaria is prevalent in tropical and
subtropical regions because rainfall, warm temperatures, and stagnant
waters provide habitats ideal for mosquito larvae. Disease transmission can
be reduced by preventing mosquito bites by using mosquito nets and insect
repellents, or with mosquito-control measures such as spraying insecticides


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