how are rna and mrna related

Messenger RNA - Wikipedia, the free encyclopedia


** Messenger RNA **

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The "life cycle" of an *mRNA* in a eukaryotic cell. RNA is transcribed in
the nucleus; processing, it is transported to the cytoplasm and translated
by the ribosome. Finally, the mRNA is degraded.

*Messenger RNA* (*mRNA*) is a large family of RNA molecules that convey
genetic information from DNA to the ribosome, where they specify the amino
acid sequence of the protein products of gene expression. Following
transcription of primary transcript mRNA (known as pre-mRNA) by RNA
polymerase, processed, mature mRNA is translated into a polymer of amino
acids: a protein, as summarized in the central dogma of molecular biology.

As in DNA, mRNA genetic information is in the sequence of nucleotides,
which are arranged into codons consisting of three bases each. Each codon
encodes for a specific amino acid, except the stop codons, which terminate
protein synthesis. This process of translation of codons into amino acids
requires two other types of RNA: Transfer RNA (tRNA), that mediates
recognition of the codon and provides the corresponding amino acid, and
ribosomal RNA (rRNA), that is the central component of the ribosome's
protein-manufacturing machinery.

The existence of mRNA was first suggested by Jacques Monod and François
Jacob, and subsequently discovered by Jacob, Sydney Brenner and Matthew
Meselson at the California Institute of Technology in 1961.


· 1 Synthesis, processing and function

· 1.1 Transcription
· 1.2 Eukaryotic pre-mRNA processing

· 1.2.1 5' cap addition
· 1.2.2 Splicing
· 1.2.3 Editing
· 1.2.4 Polyadenylation

· 1.3 Transport
· 1.4 Translation

· 2 Structure

· 2.1 5' cap
· 2.2 Coding regions
· 2.3 Untranslated regions


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