Enzymes & Substrates

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Reaction Biology Enzymes/Substrates
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Assay Services
Kinase
HMT/DNMT
HDAC/HAT
Demethylase
Bromodomain
Protease
CYP/hERG
DUB
PDE
Phosphatase
Compounds
Other Services
Proteins
Methyltransferase
Bromodomain
Cell
Cell Lines
Screening
Applications
Mapper
KIR Data

** Methyltransferase proteins: **

 

Reaction Biology Corporation (RBC) now offers an expanding line of active,
human recombinant HMTs. As the premier provider of HMT profiling and HTS
services RBC is uniquely placed to develop and deliver recombinant HMT
enzymes that are not only active but compatible with HTS assay conditions.
In RBC’s experience, many published recombinant HMT constructs and
commercially available HMTs require high enzyme concentrations, saturating
substrate levels and lengthy sample processing (e.g.
SDS-PAGE/autoradiography; Antibody generation or substrate labeling) to
simply demonstrate methyltransferase activity. The need for such conditions
is, of course, a huge drawback for drug discovery work. RBC is committed to
producing HMTs that both our customers and RBC itself can use for valid and
economical screening and profiling assays.

 

RBC welcomes bulk pricing inquiries, requests for custom protein production
and suggestions for new HMT products at 877-347-2368 or at
sales@reactionbiology.com.

 

*Protein* *Catalog* *Quantity[ug]* *Price*
ASH1L HMT-11-131 50 $325.00
DNMT1 DMT-21-124 50 $450.00
DNMT3a DMT-21-125 50 $450.00
DNMT3b DMT-21-126 50 $450.00
DNMT3B/3L Complex DMT-22-127 10 $399.00
Dot1L HMT-11-101 50 $395.00
EZH1 Complex HMT-25-115 50 $450.00
EZH2 Complex HMT-25-114 50 $799.00
G9a HMT-11-102 50 $299.00
G9a-GLP HMT-12-104 50 $325.00
GLP HMT-11-103 50 $299.00
GST-GAR HMT-11-137 50 $299.00
Histone H2A HMT-11-146 100 $50.00
Histone H2B HMT-11-147 100 $50.00
Histone H3.3 HMT-11-134 100 $50.00
MLL1 Complex HMT-15-105 50 $499.00
MLL2 Complex HMT-15-106 50 $499.00
MLL3 Complex HMT-15-107 50


Source: www.reactionbiology.com/webapps/main/pages/Proteins.aspx

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